Ribosomal protein S11



Ribosomal protein S11 (RPS11) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It functions in selecting the correct tRNA. The images at the left and at the right correspond to one representative RPS11, i.e. the crystal structure of Ribosomal protein S11 from Thermus thermophilus (2zm6, chain K).

3D Structures of Ribosomal protein S11
Update June 2011

S11 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oto - TtRPS11 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq,  3pys,  3pyu - TtRPS11 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS11 in 30S ribosomal subunit - Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3or9, 3ora - EcRPS11 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS11 in 30S ribosomal subunit+16S RRNA

1p87, 1p6g - EcRPS11 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS11 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

2zkq – RPS11 in 40S ribosomal subunit+18S RRNA+RNA fragments - dog

S11 in small + large ribosomal subunit
1ml5 - EcRPS11 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S11 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS11 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS11 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS11 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS11 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S11 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS11 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp - TtRPS11 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2i2p, 2i2u - EcRPS11 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS11 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS11 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS11 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr- TtRPS11 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S11 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S11 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS11 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS11 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS11 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS11 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS11 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S11 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS11 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S11 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S11 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS11 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS11 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS11 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S11 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh,  2f4v, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4-  TtRPS11 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnw, 1hnx, 1hnz,  1fjg - TtRPS11 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7,  2qan,  2qal,  2qou,  2qow,  2qoy,  2qp0,  2z4k,  2z4m, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy - EcRPS11 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS11 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

3knj, 3knh - TtRPS11 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knn - TtRPS11 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S11 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf – EcRPS11 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS10 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS11 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS11 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S11 in small ribosomal subunit + elongation factor
2wri, 2wrk - TtRPS11 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS11 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS11 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

3izv – EcRPS11 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS11 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

2y0u, 2y0w, 2y0y,  2y10,  2y12,  2y14,  2y16,  2y18 - TtRPS11 in 30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

3fih - EcRPS11 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS11 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

1s1h – yRPS11 in 40S ribosomal subunit +18S RRNA+elongation factor 2 - yeast

S11 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS11 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS11 in 30S ribosomal subunit+THX+IF+16S RRNA

S11 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS11 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS11 in 30S ribosomal subunit+protein Y+16S RRNA

2xfz, 2xg1 - TtRPS11 in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA

3jyv – RPS11+RPS0+RPS2+RPS3+RPS5+RPS9+RPS13+RPS14+RPS15+RPS16+RPS18+RPS20+RPS22+RPS23+RPS29+18S RRNA+RACK1+S19E+tRNA – Cryo-EM - Thermomyces lanuginosus

1x18 – TtRPS11+TtRPS2+TtRPS7+TtRPS18+ERA GTPase+16S RRNA fragment

3j00 – EcRPS11 + 16S RRNA + FTSQ + apolipoprotein A-I

S11 in small 40S ribosomal subunit + various proteins
2xzm, 2xzn - RPS11 in 40S subunit+18S RRNA+RACK1 - Tetrahymena thermophila

3o2z, 3o30 - yRPS11 in 40S ribosomal subunit+18S RRNA+RACK1

3iz6 - RPS11 in 40S ribosomal subunit+RACK1 – wheat – Cryo-EM

S11 in part of small ribosomal subunit
3iy8 - EcRPS11+EcRPS5+EcRPS6+EcRPS9+EcRPS9 EcRPS8+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+Leishmania taretolae mRNA